In 2008-9, the artist presented a Sujet à vif at the Avignon Festival and collaborated with choreographers Olivia Grandville, Daniel Larrieu and Thierry Thieû Niang. Alongside her work as a writer, she intervenes in the public arena with projects including La Phrase à Mons, European Capital of Culture 2015, and Cadavres Exquis for Le Voyage à Nantes in 2019. In 2017, she was the recipient of a City of Geneva established writer scholarship, and was awarded a residency at L'L in Brussels. Her essay La Pensée, La Poésie et La Politique was adapted for the stage by La Comédie Française in 2020, with a new production in 2023, and will be at the Avignon Festival in the summer of 2024. Karelle Ménine teaches the semiology of the image at the Geneva school of applied arts.
In 2023, she won the literary prize of the Pittard de l'Andelyn foundation.